Humacao is a city, municipality in Puerto Rico and capital of the department of the same name located in the eastern coast of the island, north of Yabucoa; south of Naguabo; east of Las Piedras; and west of Vieques. Humacao is spread over 12 barrios and Humacao Pueblo. It is part of the San Juan-Caguas-Guaynabo Metropolitan Statistical Area.