Fuquay-Varina is a town in southern Wake County, North Carolina, United States, lying south of Holly Springs and southwest of Garner. The population was 34,152 at the 2020 census, and estimated at 48,536 as of July 2025. The hyphenated name attests to the town's history as two separate towns. Fuquay Springs and Varina merged in 1963 to create the modern town. Economically, the town initially grew due to tobacco trade and agriculture, but has seen recent population growth and real estate development due to its proximity to Research Triangle Park.