Maryville is a city in and the county seat of Nodaway County, Missouri, United States. Located in the "Missouri Point" region, the city population was 10,633, according to the 2020 Census. Maryville is home to Northwest Missouri State University and Northwest Technical School. Maryville is the second-largest city wholly within the boundaries of the 1836 Platte Purchase which expanded Missouri's borders into former Indian Territory in northwest Missouri.