Southaven is a city in DeSoto County, Mississippi, United States. It is a principal city in the Greater Memphis. The population was 54,648 at the 2020 census, and was estimated at 57,493 in 2024, making it the third-most populous city in Mississippi and the largest suburb of Memphis by population. Southaven surpassed Bartlett, Tennessee as Memphis' largest suburb by population according to the 2024 Census estimates. Southaven is traversed north to south by the I-55/I-69 freeway. The city's name derives from the fact that Southaven is located south of Whitehaven, a neighborhood in Memphis.