Fort Myers Beach is a town located on the north end of Estero Island in Lee County, Florida, United States. The town is on the Gulf of Mexico and is accessed from the mainland by a bridge over Estero Bay. It is part of the Cape Coral-Fort Myers, Florida Metropolitan Statistical Area. It was officially incorporated on December 31, 1995. The population was 5,582 at the 2020 census, down from 6,277 at the 2010 census.