Laguna Niguel is a city in Orange County, California, United States. The name Laguna Niguel is derived from the words "Laguna" and "Niguili". It also appeared in Spanish records as Nigüili, Nigüel, or Neuil from Juaneño (Acjachemem) nawil. As of the 2020 census, the population was 64,355. Laguna Niguel is located in the San Joaquin Hills in the southeastern corner of Orange County, close to the Pacific Ocean, and borders the cities of Aliso Viejo, Dana Point, Laguna Beach, Laguna Hills, Mission Viejo, and San Juan Capistrano.