American Canyon is a city in southern Napa County, California, United States, 35 miles (55 km) northeast of San Francisco, part of the San Francisco Bay Area. The 2020 census reported the city's population as 21,837. Its ZIP Code is 94503, and its area code is 707. It is in the Pacific Time time zone and observes Daylight-Saving Time. The city was incorporated in 1992.