Bethel is a city in the U.S. state of Alaska, located on the Kuskokwim River approximately 50 miles (80 km) from where the river flows into Kuskokwim Bay. It is the largest community in western Alaska and in the Unorganized Borough, as well as the eighth-largest in the state. Bethel has a population of 6,325 as of the 2020 census, up from 6,080 in 2010.